Table 4.
Basal metabolic parameters of HHTg animals untreated and treated with γ-Fe2O3/CeOx-based nanoparticles.
| Untreated | γ-Fe2O3 | γ-Fe2O3/CeOx | γ-Fe2O3/CeOx@PEG2, 000 | γ-Fe2O3/CeOx@PEG5, 000 | p | |
|---|---|---|---|---|---|---|
| Body weight (g) | 405 ± 13 | 386 ± 46 | 387 ± 25 | 417 ± 36 | 408 ± 18 | n.s. |
| Triacylglycerols (mmol/l) | 3.22 ± 0.33 | 3.47 ± 0.20 | 3.45 ± 0.46 | 3.84 ± 0.34 | 2.96 ± 0.62 | n.s. |
| Cholesterol (mmol/l) | 1.88 ± 0.10 | 2.04 ± 0.35 | 1.86 ± 0.19 | 1.98 ± 0.10 | 1.85 ± 0.12 | n.s. |
| Non-fasting glucose (mmol/l) | 8.71 ± 0.22 | 8.05 ± 1.60 | 8.13 ± 0.38 | 8.70 ± 0.44 | 7.96 ± 0.60 | n.s. |
| ALT (μkat/l) | 1.16 ± 0.12 | 1.07 ± 0.08 | 1.09 ± 0.14 | 1.04 ± 0.06 | 1.19 ± 0.50 | n.s. |
| AST (μkat/l) | 2.75 ± 0.09 | 2.41 ± 0.11 | 2.70 ± 0.48 | 2.25 ± 0.18 | 2.76 ± 0.07 | n.s. |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; p, statistical significance; n.s., not significant.