Fig. 1.

Inhibitory effect of EGCG on the HFD-induced obese phenotype and hepatic triacylglycerol accumulation. (A) Time course of mouse body weight. Body weight of male mice receiving an EGCG containing diet for 8 weeks. (B) Liver weight. (C) Hematoxylin eosin (HE)-stained liver sections. (D) Area of fatty lesions in the liver. (E) Hepatic triacylglycerol (TG) content. C57BL/6N mice were fed a CE2 diet (control), a high-fat diet (HFD), or an HFD supplemented with 0.32% EGCG (HFD + EGCG) for 8 weeks. Values are expressed as the means and SEM of eight mice in each group. Significant differences compared with the control group are denoted *p<0.05, and those with the HFD group are denoted ^†p<0.05. Photographs are of HE staining of liver sections from representative mice of each group (scale bar = 500 mm). See color figure in the on-line version. Published with permission.⁽¹⁰⁾