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. 2020 Aug 11;18(8):e06222. doi: 10.2903/j.efsa.2020.6222

Table 36.

Summary results of literature reports on total glycoalkaloids (TGA) concentrations in tomatoes

Country Year of survey Tomato N TGA average (mg/kg fw)e Range (mg/kg fw) Analytical technique Reference
UK 1984 Ripe (3 cultivars)a 3 3.7 3–6 Radioimmunoassay Eltayeb and Roddick (1984)
NL 1987 Ripea 1 5 GC‐FID and GC‐NPD Van Gelder and De Ponti (1987)
NL 1994 Redb 14 0.6 < 0.5–4.1 HPLC‐UV Keukens et al. (1994)
Orangeb 14 6.2 < 0.5–18.2
Greenb 14 26 4.5–90
USA 1994 Red (5 cultivars)b 99 < 2.5–23 (94 are ND) HPLC‐UV Bushway et al. (1994)
Green (4 cultivars)b 80 18.3 < 2.5–88
USA 1994–2004 Red, conventional (3 cultivars)c 54 1.16f < 0.05–5.6f LC‐MS/MS Koh et al. (2013)
Red, organic (3 cultivars)c 54 2.11f < 0.05–4.9f
USA 1994 Red, riped 4 1.1 0.3–2.8 HPLC‐UV/HPLC‐PAD Friedman et al. (1994)
Reda 2 2.7 1.5–3.9
Breakera 1 16.5
Green, maturea 1 45
Green, immaturea 1 69
USA 1995 Red, yellow, ripe (8 cultivars)d 8 3.6 0.3–11 HPLC‐PAD Friedman and Levin (1995)
Green, unriped 1 16
Reda 2 1.8 1.2–2.5
Breakera 2 10.5 6.7–14
Green, maturea 2 40 25–58
Green, immaturea 2 125 40–210
JP 1997 Green, maturea 7 165 140–180 Colourimetric Furui et al. (1997)
Turninga 4 44 30–60
Red, maturea 6 3 1–8
USA 1998 Reda 15 1.4 0.4–4.3 HPLC‐PAD Friedman and Levin (1998)
Green, immaturea 15 205 35–550
IT 2000 Green‐orange, reda 5 15 ND–43 HPLC‐UV Leonardi et al. (2000)
IL 2006 Ripeningc 3 2.5f 0–6.7f HPLC‐UV Mulatu et al. (2006)
Green, maturec 3 0.65f 0–1.4f
Green, immaturec 3 1.4f 0.13–3.5f
JP
IT 2016 Ripe (15 landraces and 3 hybrids)c 18

1.5g

5.1h

0.6–4.0g

1.8–14.2h

LC‐HRMS Baldina et al. (2016)
IT 2019 Various ripening stagesd 3 1.1g 0.49–2.0g LC‐MS/MS Tamasi et al. (2019)

TGA: total glycoalkaloids; LC: liquid chromatography; UV: ultraviolet; MS: mass spectrometry; MS/MS: tandem MS; HR: high resolution; HP: high‐performance; PAD: Pulsed amperometric detector; FID: flame ionisation detector. NPD: nitrogen‐phosphorous detector.

a

Greenhouse.

b

Wholesale.

c

Field trial.

d

Retail.

e

Average as reported by the authors or calculated based on the provided individual data.

f

Data were presented as dry weight. It has been assumed that the water content was 95%.

g

Results for α‐tomatine + α‐dehydrotomatine.

h

Results for all 7 GAs analysed (α‐tomatine, dehydrotomatine, esculeoside A, lycoperosides A, B and H and tomatoside A).