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. 2020 Aug 11;18(8):e06222. doi: 10.2903/j.efsa.2020.6222

Table E.2.

Determined Ki values

Compound Species AChE BuChE
Ki (μM) Ki (μM) Citation
α‐Solanine Human plasma 5 Orgell (1963)
α‐Tomatine Human plasma 100
Chaconine (TLC preparation) Purified bovine cholinesterase 8,3 Alozie et al. (1978)
Horse serum cholinesterase 4
α‐Chaconine equine BuChE 1.39 Benilova et al. (2006)
α‐Solanine equine BuChE 3.33
α‐Tomatine equine BuChE 1.66
α‐Chaconine human BuChE 0.17
α‐Solanine human BuChE 0.22
α‐Tomatine human BuChE 1.3
α‐Solanine Human serum (D/D; wild type, homozygous) 2.9 Sternfeld et al. (1997)
α‐Solanine Human serum (D/G; heterozygous) 3.6
α‐Solanine Human serum (G/G; homozygous) 165
α‐Solanine Human recombinant (D/D; wild type, homozygous) 2.0
α‐Solanine Human recombinant (D/G; heterozygous) 3.5
α‐Solanine Human recombinant (G/G; homozygous) 171
α‐Solanine Human, purified 14 0.17 McGehee et al. (2000)
α‐Chaconine Human, purified 17 0.066
α‐Solanine Human wild type 3.3 Loewenstein‐Lichtenstein et al. (1996)
α‐Solanine Human atypical (D70G) 78
α‐Solanine Various artificial mutations 0.3–78