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A set of experimental drugs targeting S1A serine proteases that may inhibit TMPRSS2 and are modelled in Fig. 3.
| Drugbank ID | Crystallized Protein | PDB ID | Notes |
|---|---|---|---|
| DB04442 | Trypsin | 1GHZ | |
| DB03082 | uPA | 1SQA | Abbott compound |
| DB08697 | uPA | 2VIV | Astex compound |
| DB07247 | Factor VII | 2FLR | |
| DB03782 | uPA | 1EJN | |
| DB02398 | uPA | 1OWH | |
| DB03865 | Hepsin | 1O5E | Trypsin/thrombin/uPA/hepsin inhibitor |
| DB01725 | uPA | 1GJC | Trypsin/thrombin/uPA inhibitor |
