Table 3.
Basal level of the cytokine profile from healthy controls and patients with atopic dermatitis.
| Healthy subject (n = 7) | AD patient (n = 10) | p value | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| IL-1β | 0.4 | ±0.4 | 1.1 | ±1.6 | 0.732 |
| IL-1ra | 312.3 | ±571.7 | 680.5 | ±612.1 | 0.040∗ |
| IL-2 | 1.9 | ±1.5 | 2.2 | ±1.3 | 0.557 |
| IL-4 | 0.3 | ±0.2 | 0.5 | ±0.4 | 0.435 |
| IL-5 | 0.8 | ±1.2 | 0.8 | ±1.2 | 0.913 |
| IL-6 | 1.5 | ±1.2 | 1.2 | ±0.7 | 0.733 |
| IL-7 | 0.7 | ±1.9 | 3.2 | ±4.8 | 0.101 |
| IL-8 | 20.7 | ±5.2 | 70.2 | ±87.4 | 0.845 |
| IL-9 | 7.0 | ±5.5 | 12.3 | ±12.2 | 0.526 |
| IL-10 | 2.0 | ±1.0 | 2.7 | ±1.7 | 0.435 |
| IL-12 (p70) | 3.0 | ±2.1 | 2.1 | ±1.8 | 0.464 |
| IL-13 | 0.3 | ±0.4 | 1.5 | ±2.1 | 0.157 |
| IL-15 | 9.6 | ±8.9 | 10.9 | ±9.2 | 0.696 |
| IL-17A | 11.5 | ±5.4 | 7.3 | ±3.8 | 0.051 |
| Eotaxin | 2.7 | ±1.6 | 3.0 | ±2.3 | 0.884 |
| Basic FGF | 27.7 | ±11.4 | 30.8 | ±19.6 | 0.626 |
| G-CSF | 11.4 | ±19.8 | 12.4 | ±9.3 | 0.187 |
| GM-CSF | 92.3 | ±44.4 | 90.7 | ±65.0 | 0.626 |
| IFN-γ | 4.3 | ±6.4 | 5.9 | ±3.7 | 0.239 |
| IP-10 | 1.4 | ±2.7 | 1.2 | ±2.0 | 0.819 |
| MCP-1 | 122.7 | ±76.4 | 66.8 | ±63.8 | 0.079 |
| MIP-1α | 15.0 | ±17.1 | 25.2 | ±29.7 | 0.558 |
| MIP-1β | 45.9 | ±44.2 | 81.8 | ±98.8 | 0.922 |
| PDGF-BB | 3.7 | ±2.1 | 5.9 | ±5.9 | 0.695 |
| RANTES | 17.3 | ±35.6 | 5.5 | ±2.5 | 0.406 |
| TNF-α | 6.3 | ±10.6 | 2.6 | ±1.8 | 0.806 |
| VEGF | 28.0 | ±35.6 | 19.7 | ±23.3 | 0.625 |
Data are expressed as the mean ± standard deviation. Data were analyzed using the Wilcoxon signed-rank test.