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. 2020 Aug 6;12:857–864. doi: 10.2147/CLEP.S256662

Table 1.

Incidence of Common Cancers as First Primary Cancer and Second Primary Cancer, and Respective Relative Risk (RR) in Men

First Primary Cancer Second Primary Cancer After Invasive SCC
Cancer Number of Cases Standardized Rate 1/100,000 Rank1 Number of Cases Standardized Rate 2/100,000 Rank2 RR 95% CI
Prostate 185,081 95.2 1 1483 110.4 1 1.16 1.10 1.22
Colorectum 60,037 32.2 2 545 42.5 3 1.32 1.21 1.44
Lung 41,165 23.5 3 372 40.9 4 1.74 1.57 1.93
Bladder 35,818 18.9 4 374 26.5 7 1.40 1.27 1.55
Melanoma 22,812 14.7 5 355 47.5 2 3.23 2.91 3.60
Leukemia 17,318 11.3 6 180 21.7 8 1.92 1.66 2.23
NHL 18,414 11.3 7 237 26.8 6 2.37 2.08 2.70
Nervous system 14,199 11.1 8 45 15.0 9 1.35 1.01 1.81
Kidney 13,922 8.7 9 98 13.3 10 1.53 1.26 1.87
Stomach 13,800 7.3 10 152 12.4 11 1.70 1.44 1.99
UAT 11,371 7.2 11 195 27.3 5 3.79 3.29 4.38
Liver 10,990 6.3 12 82 8.8 12 1.39 1.12 1.72
Myeloma 7202 4.0 13 52 4.6 14 1.15 0.88 1.51
Endocrine 5558 3.9 14 16 3.9 15 0.99 0.60 1.62
Connective tissue 3564 2.4 15 46 6.3 13 2.64 1.97 3.54
Hodgkin lymphoma 2399 2.0 16 8 3.8 16 1.91 0.95 3.85
Thyroid 2213 1.6 17 10 2.3 18 1.45 0.78 2.71
Small intestine 2423 1.5 18 21 2.5 17 1.65 1.07 2.54
Male genital 1835 1.1 19 22 2.1 19 1.94 1.27 2.96
Breast 803 0.5 20 14 1.3 20 2.62 1.54 4.47
All* 515,982 256.0 4662 376.3 1.47 1.43 1.51

Notes: *Skin cancer is removed from all cancers; some rare cancers, not listed in Table 1 are included. Bolding shows RRs>2.00.

Abbreviations: SCC, squamous cell carcinoma; NHL, non-Hodgkin lymphoma; UAT, upper aerodigestive tract.