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. 2020 Aug 6;12:857–864. doi: 10.2147/CLEP.S256662

Table 2.

Incidence of Common Cancers as First Primary Cancer and Second Primary Cancer, and Respective Relative Risk (RR) in Women

First Primary Cancer Second Primary Cancer After Invasive SCC
Cancer Number of Cases Standardized Rate 1/100,000 Rank1 Number of Cases Standardized Rate 2/100,000 Rank2 RR 95% CI
Breast 143,819 83.6 1 529 103.7 1 1.24 1.14 1.35
Colorectum 56,198 24 2 354 30.0 3 1.25 1.13 1.39
Lung 31,306 16.4 3 136 22.1 4 1.35 1.14 1.60
Melanoma 23,800 15.2 4 181 39.7 2 2.61 2.25 3.02
Endometrium 28,548 14.7 5 134 19.0 5 1.29 1.09 1.53
Nervous system 16,042 11.5 6 19 7.5 10 0.65 0.41 1.02
Ovary 18,523 11 7 68 15.4 7 1.40 1.10 1.77
Leukemia 13,833 7.9 8 95 13.4 9 1.69 1.38 2.07
Cervix 11,053 7.7 9 19 7.4 11 0.96 0.61 1.51
NHL 15,152 7.6 10 132 15.9 6 2.09 1.76 2.48
Endocrine 11,393 7.2 11 20 5.5 14 0.77 0.49 1.19
Bladder 12,134 5.2 12 83 6.9 12 1.33 1.07 1.65
Kidney 9520 5 13 32 5.0 15 0.99 0.70 1.40
Liver 10,939 4.8 14 52 5.7 13 1.18 0.90 1.55
Thyroid 5758 4.1 15 9 3.3 19 0.81 0.42 1.57
Stomach 8889 3.7 16 50 4.5 16 1.22 0.92 1.61
UAT 6932 3.7 17 105 13.6 8 3.68 3.03 4.47
Myeloma 5898 2.6 18 27 2.6 21 1.00 0.69 1.47
Female genital 4450 1.9 19 44 3.5 18 1.86 1.38 2.51
Connective tissue 2903 1.8 20 17 3.2 20 1.76 1.09 2.84
Hodgkin lymphoma 1934 1.7 21 6 3.7 17 2.20 0.98 4.93
Small intestine 2112 1 22 7 0.8 22 0.83 0.39 1.74
All* 481,702 237.7 2371 325.6 1.37 1.32 1.43

Notes: *Skin cancer is removed from all cancers; some rare cancers, not listed in Table 2 are included. Bolding shows RRs>2.00.

Abbreviations: SCC, squamous cell carcinoma; NHL, non-Hodgkin lymphoma; UAT, upper aerodigestive tract.