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. 2020 Jul 10;21:751–763. doi: 10.1016/j.omtn.2020.07.013

Figure 3.

Figure 3

p66Shc Contributes to HSC Proliferation during Liver Fibrosis and Is Modulated by CA

(A and B) The percentage of LX-2 cells in the G1 phase in different groups; n = 3. ∗∗p < 0.01 versus the control group; ##p < 0.01 versus the PDGF-BB group. (C) CCK8 assays were used to examine cell proliferation at the indicated time points; n = 6. ∗∗p < 0.01 versus the control group; #p < 0.05 versus the PDGF-BB group; ##p < 0.01 versus the PDGF-BB group. (D) Cyclin D1 and p21 protein expression in LX-2 cells; n = 3. ∗∗p < 0.01 versus the control group; ##p < 0.01 versus the PDGF-BB group in different groups. (E) Immunofluorescence images (×200) showing mitochondrial ROS (red) production in LX-2 cells. Hoechst was used as a counterstain.