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. 2020 Aug 10;3(8):e2012749. doi: 10.1001/jamanetworkopen.2020.12749

Table 1. Baseline Characteristics of Patients Included in Final Analysis Stratified by Original Treatment Recommendation Received.

Characteristic Original treatment, No. (%) P value for 3-way comparison
Overall (n = 234) CABG (n = 148) PCI (n = 71) Medication therapy (n = 15)
Age, mean (SD), y 67.8 (10.9) 66.7 (9.7) 68.3 (12.7) 74.9 (10.5) .02
Male sex 176 (75.2) 116 (78.4) 51 (71.8) 9 (60.0) .21
Treatment indication
Stable CAD or angina 97 (41.5) 69 (46.6) 21 (29.6) 7 (46.7) .18
Unstable angina or non-STEMI 123 (52.6) 69 (46.6) 46 (64.8) 8 (53.3)
Reperfused STEMI 2 (0.9) 1 (0.7) 1 (1.4) 0
Ventricular arrhythmia 3 (1.3) 1 (0.7) 2 (2.8) 0
Cardiomyopathy or CHF 9 (3.8) 8 (5.4) 1 (1.4) 0
Comorbidities
Previous MI 38 (16.2) 21 (14.2) 12 (16.9) 5 (33.3) .16
Diabetes 99 (42.3) 72 (48.6) 21 (29.6) 6 (40) .03
Renal dysfunction 44 (18.8) 25 (16.9) 16 (22.5) 3 (20.0) .62
Dialysis 9 (3.8) 8 (5.4) 1 (1.4) 0 .26
COPD 18 (7.7) 9 (6.1) 7 (9.9) 2 (13.3) .43
Previous stroke 27 (11.5) 16 (10.8) 10 (14.1) 1 (6.7) .65
Cognitive dysfunction 11 (4.7) 3 (2.0) 7 (9.9) 1 (6.7) .04
Angiographic characteristics
3VD 191 (81.6) 133 (89.9) 44 (62.0) 14 (93.3) <.001
2VD with prox LAD 43 (18.4) 15 (10.1) 27 (38.0) 1 (6.7)
Test results, mean (SD)
LV function ejection fraction, % 49.2 (11.2) 48.4 (11.1) 51.3 (11.0) 46.8 (12.4) .15
BMI 29.6 (6.8) 30.1 (6.0) 29.8 (8.0) 24.1 (5.4) .005
SYNTAX score 28.6 (10.7) 30.9 (10.4) 23.5 (9.9) 29.2 (9.6) <.001
EuroSCORE 2.2 (2.4) 1.9 (1.9) 2.4 (2.9) 3.9 (4.0) .006
STS score
Mortality 1.6 (1.7) 1.4 (1.5) 1.8 (2.0) 2.8 (1.7) .005
Morbidity and mortality 12.0 (8.4) 11.8 (7.7) 11.6 (9.5) 17.0 (8.9) .11

Abbreviations: 2VD with prox LAD, 2 epicardial coronary vessels with involvement of the proximal left anterior descending artery; 3VD, 3 epicardial coronary vessels; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CABG, coronary artery bypass grafting; CAD, coronary artery disease; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; EuroSCORE, European System for Cardiac Operative Risk Evaluation score; LV, left ventricular; MI, myocardial infarction; PCI, percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction; STS, Society of Thoracic Surgeons; SYNTAX, Synergy Between PCI With Taxus and Cardiac Surgery clinical trial.