Table 1. Baseline Characteristics of Patients Included in Final Analysis Stratified by Original Treatment Recommendation Received.
Characteristic | Original treatment, No. (%) | P value for 3-way comparison | |||
---|---|---|---|---|---|
Overall (n = 234) | CABG (n = 148) | PCI (n = 71) | Medication therapy (n = 15) | ||
Age, mean (SD), y | 67.8 (10.9) | 66.7 (9.7) | 68.3 (12.7) | 74.9 (10.5) | .02 |
Male sex | 176 (75.2) | 116 (78.4) | 51 (71.8) | 9 (60.0) | .21 |
Treatment indication | |||||
Stable CAD or angina | 97 (41.5) | 69 (46.6) | 21 (29.6) | 7 (46.7) | .18 |
Unstable angina or non-STEMI | 123 (52.6) | 69 (46.6) | 46 (64.8) | 8 (53.3) | |
Reperfused STEMI | 2 (0.9) | 1 (0.7) | 1 (1.4) | 0 | |
Ventricular arrhythmia | 3 (1.3) | 1 (0.7) | 2 (2.8) | 0 | |
Cardiomyopathy or CHF | 9 (3.8) | 8 (5.4) | 1 (1.4) | 0 | |
Comorbidities | |||||
Previous MI | 38 (16.2) | 21 (14.2) | 12 (16.9) | 5 (33.3) | .16 |
Diabetes | 99 (42.3) | 72 (48.6) | 21 (29.6) | 6 (40) | .03 |
Renal dysfunction | 44 (18.8) | 25 (16.9) | 16 (22.5) | 3 (20.0) | .62 |
Dialysis | 9 (3.8) | 8 (5.4) | 1 (1.4) | 0 | .26 |
COPD | 18 (7.7) | 9 (6.1) | 7 (9.9) | 2 (13.3) | .43 |
Previous stroke | 27 (11.5) | 16 (10.8) | 10 (14.1) | 1 (6.7) | .65 |
Cognitive dysfunction | 11 (4.7) | 3 (2.0) | 7 (9.9) | 1 (6.7) | .04 |
Angiographic characteristics | |||||
3VD | 191 (81.6) | 133 (89.9) | 44 (62.0) | 14 (93.3) | <.001 |
2VD with prox LAD | 43 (18.4) | 15 (10.1) | 27 (38.0) | 1 (6.7) | |
Test results, mean (SD) | |||||
LV function ejection fraction, % | 49.2 (11.2) | 48.4 (11.1) | 51.3 (11.0) | 46.8 (12.4) | .15 |
BMI | 29.6 (6.8) | 30.1 (6.0) | 29.8 (8.0) | 24.1 (5.4) | .005 |
SYNTAX score | 28.6 (10.7) | 30.9 (10.4) | 23.5 (9.9) | 29.2 (9.6) | <.001 |
EuroSCORE | 2.2 (2.4) | 1.9 (1.9) | 2.4 (2.9) | 3.9 (4.0) | .006 |
STS score | |||||
Mortality | 1.6 (1.7) | 1.4 (1.5) | 1.8 (2.0) | 2.8 (1.7) | .005 |
Morbidity and mortality | 12.0 (8.4) | 11.8 (7.7) | 11.6 (9.5) | 17.0 (8.9) | .11 |
Abbreviations: 2VD with prox LAD, 2 epicardial coronary vessels with involvement of the proximal left anterior descending artery; 3VD, 3 epicardial coronary vessels; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CABG, coronary artery bypass grafting; CAD, coronary artery disease; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; EuroSCORE, European System for Cardiac Operative Risk Evaluation score; LV, left ventricular; MI, myocardial infarction; PCI, percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction; STS, Society of Thoracic Surgeons; SYNTAX, Synergy Between PCI With Taxus and Cardiac Surgery clinical trial.