Figure. Magnetic Resonance Imaging Features of Patients With Myelin Oligodendrocyte Glycoprotein–IgG Associated Disorders Meeting and Not Meeting the Neuromyelitis Optica Spectrum Disorder (NMOSD) 2015 Seronegative Criteria.

Meeting NMOSD 2015 Seronegative criteria: patient 1 (A) sagittal magnetic resonance imaging (MRI) T2 longitudinally extensive conus lesion (first attack), sagittal MRI T2 longitudinally extensive thoracic lesion from T7-T10 (B; second attack), and axial MRI with T2/fluid-attenuated inversion recovery periepenydmal brainstem lesion (C).

Not meeting NMOSD 2015 seronegative criteria: patient 2 (D) axial MRI T2/fluid-attenuated inversion recovery large bilateral subcortical and periventricular lesions in the setting of acute disseminated encephalomyelitis in patient with history of recurrent optic neuritis. Patient 3 (E) axial MRI with brainstem medullary T2 lesion (not peripendymal) in a patient with recurrent optic neuritis.