Table 2. Multivariable Assessments of Scores on Psychological Scales Postdisclosure^a.

Characteristic	Δ in GDS		Δ in STAI		IES
	Estimate (SE)	P value	Estimate (SE)	P value	Estimate (SE)	P value
Intercept	–1.31 (0.51)	.01	0.38 (1.17)	.75	18.29 (3.73)	<.001
Groupsb	–0.01 (0.07)	.90	–0.07 (0.16)	.65	4.35 (0.53)	<.001
Age	0.02 (0.01)	.01	–0.00 (0.02)	.95	–0.17 (0.05)	<.001
CFI	–0.02 (0.02)	.18	–0.02 (0.04)	.63	0.33 (0.11)	.004
Sexc	–0.00 (0.07)	.95	–0.20 (0.15)	.19	–3.32 (0.49)	<.001
Family historyd	0.05 (0.07)	.47	–0.34 (0.17)	.04	0.84 (0.54)	.12

Abbreviations: CFI, Cognitive Function Instrument; GDS, Geriatric Depression Scale; IES, Impact of Events Scale; STAI, State-Trait Anxiety Inventory.

^aModels include change between visit 1 and visit 6 for the GDS and STAI. Results are from an analysis of covariance model with the change score as the dependent variable and group as the main independent variable, adjusting for age, screening CFI score, sex, and family history of Alzheimer disease. For IES, models include data collected at a single point after visit 3. Results are from an analysis of covariance model with IES visit 6 score as the dependent variable and group as the main independent variable, adjusting for age, screening CFI score, sex, and family history of Alzheimer disease.

^bReferent: elevated amyloid group.

^cReferent: male sex.

^dReferent: a family history positive for Alzheimer disease.