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. 2020 Aug 11;370:m2724. doi: 10.1136/bmj.m2724

Table 1.

Characteristics of participants at entry, and of participants with atrial fibrillation at diagnosis, in each time period

All participants Participants with atrial fibrillation
Time period 1 (1972-85; n=5671) Time period 2 (1986-2000; n=6177) Time period 3 (2001-15; n=6174) Time period 1 (1972-85; n=305) Time period 2
(1986-2000; n=596)
Time period 3 (2001-15; n=468)
Age (years) 59.0 (10.5) 59.9 (12.2) 61.0 (12.5) 74.4 (9.5) 76.6 (10.5) 77.8 (10.7)
Sex (% women) 54.6 (n=3094) 56.2 (n=3474) 56.7 (n=3501) 48.2 (n=147) 45.8 (n=273) 45.7 (n=214)
Education (%)
 No high school degree 26.6 (n=1415) 15.3 (n=867) 4.9 (n=278) 42.5 (n=122) 28.6 (n=160) 10.5 (n=47)
 High school degree only 34.1 (n=1810) 31.2 (n=1776) 23.7 (n=1353) 28.9 (n=83) 33.1 (n=185) 32.7 (n=147)
 Some college 21.3 (n=1130) 25.2 (n=1435) 29.6 (n=1685) 16.7 (n=48) 30.6 (n=115) 22.5 (n=101)
 College graduate 18.0 (n=956) 28.3 (n=1610) 41.8 (n=2380) 11.9 (n=34) 17.7 (n=99) 34.3 (n=154)
Systolic blood pressure (mm Hg) 134 (21) 132 (21) 126 (18) 145 (23) 142 (22) 135 (20)
Diastolic blood pressure (mm Hg) 80 (11) 78 (10) 75 (10) 77 (12) 74 (11) 71 (11)
Hypertension treatment (%) 18.9 (n=1070) 26.3 (n=1616) 36.3 (n=2227) 44.4 (n=134) 56.5 (n=331) 65.3 (n=303)
Body mass index 26.4 (4.3) 27.0 (4.9) 28.1 (5.6) 26.3 (4.5) 27.7 (4.9) 28.8 (5.6)
Current smoker (%) 32.1 (n=1789) 20.0 (n=1230) 10.3 (n=635) 20.1 (n=59) 12.5 (n=74) 6.6 (n=31)
Diabetes mellitus (%) 5.7 (n=304) 6.8 (n=402) 10.8 (n=628) 12.3 (n=35) 17.7 (n=83) 22.6 (n=92)
Total cholesterol (mmol/L) 5.8 (1.1) 5.6 (1.1) 4.9 (0.9) 5.7 (1.3) 5.2 (1.1) 4.6 (0.9)
Use of statins (%) 1.8 (n=99) 3.2 (n=198) 28.7 (n=1771) 1.7 (n=5) 8.1 (n=48) 48.5 (n=227)
Previous heart failure (%) 1.1 (n=62) 1.2 (n=75) 1.0 (n=64) 8.5 (n=26) 6.7 (n=40) 4.5 (n=21)
Previous myocardial infarction (%) 4.7 (n=265) 4.7 (n=287) 3.5 (n=213) 15.1 (n=46) 15.1 (n=90) 8.8 (n=41)
Previous stroke or transient ischemic attack (%) 2.4 (n=133) 3.1 (n=194) 3.0 (n=184) 12.5 (n=38) 10.6 (n=63) 8.8 (n=41)

Data are mean (standard deviation) or percentage (frequency). Corresponding percentages of missing values for time periods 1, 2, and 3, respectively: body mass index=1.0%, 3.7%, and 6.1%; systolic blood pressure=0.1%, 0.1%, and 0.2%; diastolic blood pressure=0.1%, 0.1%, and 0.2%; current smoker=1.7%, 0.2%, and 0.1%; diabetes mellitus=6.1%, 4.5%, and 6.2%; hypertension treatment=0.3%, 0.4%, and 0.6%; total cholesterol=3.8%, 5.7%, and 6.1%; use of statins=0.1%, 0.2%, and 0.2%; education=6.3%, 7.9%, and 7.7%.