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. Author manuscript; available in PMC: 2020 Aug 11.
Published in final edited form as: Cell Rep. 2020 Jun 23;31(12):107804. doi: 10.1016/j.celrep.2020.107804

Figure 7. Estimating In Vivo Cell Cycle Length from H2B-FT BR.

Figure 7.

(A and B) Cell cycle length distribution of n = 215 GMPs determined by time-lapse microscopy and BR distribution as analyzed by flow cytometry. Dotted lines show indicated percentiles.

(C) Calculated cell cycle length distributions of BM populations from a representative iH2B-FT mouse.

(D) Cell cycle length distribution of L-GMPs driven by MLL-ENL versus normal GMPs.

(E) Median cell cycle length variation among n = 3 iH2B-FT mice, shown by percentage coefficient of variation (CV%).

(F) Cell cycle length distributions of LKS and GMP from the individual mice in (E).

Boxes in (C), (D), and (F) represent median and IQR of each group; whiskers, 5th–95th percentiles. See also Figure S7.