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. 2020 Aug 6;12:6779–6793. doi: 10.2147/CMAR.S264681

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© 2020 Zhang et al.

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miR-324-5p inhibition reverses the impacts of LINC00491 depletion on NSCLC cells. (A) The expression of miR-324-5p was detected in H522 and SK-MES-1 cells transfected with anti-miR-324-5p or anti-miR-NC. (B–E) CCK-8 assay, flow cytometry analysis, and migration and invasion detection assays were carried out to, respectively, determine the proliferation, apoptosis, migration, and invasion of H522 and SK-MES-1 cells after cotransfection with anti-miR-324-5p or anti-miR-NC and si-LINC00491. *P < 0.05 and **P < 0.01.

Abbreviations: LINC00491, long intergenic non-protein coding RNA 491; si-LINC00491, LINC00491-specific small interfering RNA; si-NC, negative control small interfering RNA; PI, propidium iodide; miR-324-5p, microRNA-324-5p; anti-miR-NC, negative control miRNA inhibitor; anti-miR-324-5p, miR-324-5p inhibitor.