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. 2020 Aug 10;20:122. doi: 10.1186/s12902-020-00605-5

Table 3.

Relative risk of new onset diabetic complications by patient characteristics

Characteristics Composite complications RR (95% CI)
Age 1.006 (1.005–1.007)a
Men (Ref. women) 0.93 (0.92–0.95)a
CCI 1.018 (1.013–1.023)a
Baseline DCSI 1.26 (1.25–1.27)a
Insulin 1.07 (1.03–1.11)a
Aspirin 1.07 (1.06–1.09)a
Clopidogrel 0.96 (0.94–0.98)a
Sarpogrelate 1.00 (0.97–1.02)
Cilostazol 0.99 (0.95–1.03)
ACEI/ARB 0.99 (0.98–1.01)
Statin 0.92 (0.91–0.93)a
Number of antidiabetics
 1 Reference
 2 1.01 (1.00–1.03)
 3 + 1.13 (1.10–1.17)a
Antidiabetics therapy
 Mono therapy
  Metformin Reference
  DPP4-I 0.77 (0.70–0.85)a
  Sulfonylurea 1.29 (1.27–1.32)a
  Glucosidase 1.25 (1.18–1.33)a
 Dual therapy
  Metformin + Sulfonylurea Reference
  Metformin + DPP4-I 0.71 (0.69–0.73)a

Abbreviation: CCI Charlson comorbidity index score, ACEI/ARB angiotensin-1 converting enzyme Inhibitor/angiotensin-2 receptor blocker, DPP4-I dipeptidyl peptidase-4 inhibitor

a statistically significant