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. 2020 Aug 10;40(8):BSR20201223. doi: 10.1042/BSR20201223

Figure 5. Knockdown of TRIM52 represses TLR4/NF-κB pathway in LPS-treated HPDLCs.

Figure 5

HPDLCs were transfected with si-TRIM52 or si-NC, and then exposed them to LPS or PBS. (A,B) qRT-PCR analysis showing that knockdown of TRIM52 attenuated LPS-induced elevation of TLR4 and NF-κB p65 expression in HPDLCs. (C) Western blot analysis showing that knockdown of TRIM52 attenuated LPS-induced elevation of TLR4, p-TAK1, p-IKK-α/β, p-IκBα and NF-κB p65 protein levels in HPDLCs. *P<0.05, **P<0.01 and ***P<0.001.