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. 2020 Aug 11;45(6):715–723. doi: 10.1007/s13318-020-00640-6

Fig. 2.

Fig. 2

Simulation plots under k = 1/day, T = 4e8 (initial value [24]),  = 1.65/day, p = 2e4 [46], β = 8.24 × 10e−3 [21] and V0 at initial {11, 103, 106} copies/ml describing the dynamics of reduction in viral load under six drug efficacy (ɛ) conditions. Baseline conditions with ε = 0, ε = 33%, ε = 62.3%, ε = 70% and ε = 78%. The results obtained should be compared with the first row of graphs in Fig. 1, simulating a condition in the absence of chloroquine/hydroxychloroquine. The first row of the present figure instead aims at simulating the effect of a drug or intervention able to increase the death of infected cells but having no antiviral effect per se