Fig. 4.

Immunoblotting of TH and DAT in the striatum after intranasal delivery of vehicle (VEH) or dopamine (DA). a Western blots of striatal lysates from BTBR mice treated with VEH or DA. Increased TH expression was found after DA administration. b Western blots of striatal lysates from Fmr1-KO mice treated with VEH or DA. Reduced TH level was noticed after DA application. In both cases, DAT protein was unaltered by intranasal DA. TH: tyrosine hydroxylase; DAT: dopamine transporter. n = 5–6 mice/group. *p < 0.05, compared to VEH