Table 3.
Univariate and Multivariable Analysis of Factors Associated with TBI Treatment Initiation
| Univariate | Multivariable | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p | OR | 95% CI | p | |
| Elixhauser Comorbidity Indexa | ||||||
| No Comorbidity (Score = 0) | ref | |||||
| Any Comorbidity (Score ≥ 1) | 0.79 | [0.60,1.05] | 0.11 | |||
| Diabetesa | ||||||
| No | ref | |||||
| Yes | 0.68 | [0.31,1.48] | 0.34 | |||
| Hypertensiona | ||||||
| No | ref | |||||
| Yes | 0.54 | [0.33,0.88] | 0.01 | 0.64 | [0.37,1.10] | 0.10 |
| Liver Diseasea | ||||||
| No | ref | |||||
| Yes | 0.94 | [0.54,1.65] | 0.83 | |||
| HIVa | ||||||
| No | ref | |||||
| Yes | 1.17 | [0.31,4.43] | 0.82 | |||
| Screening Test | ||||||
| Tuberculin Skin Test | ref | |||||
| Interferon Gamma Release Assay | 1.88 | [1.33,2.67] | < 0.001 | 2.89 | [1.59,5.27] | 0.001 |
| Year of Arrival | ||||||
| 2012 | ref | |||||
| 2013 | 2.17 | [1.49,3.18] | < 0.001 | 1.14 | [0.66,1.99] | 0.64 |
| 2014 | 1.42 | [0.96,2.12] | 0.08 | 0.72 | [0.39,1.33] | 0.29 |
| 2015 | 1.41 | [0.94,2.12] | 0.09 | 0.66 | [0.36,1.21] | 0.18 |
| 2016 | 0.73 | [0.47,1.14] | 0.17 | 0.40 | [0.21,0.74] | 0.004 |
| Family Size at Time of Entry | ||||||
| Single | ref | |||||
| Family of 2–3 | 0.82 | [0.58,1.14] | 0.23 | 1.04 | [0.71,1.52] | 0.83 |
| Family of > 3 | 0.73 | [0.53,0.99] | 0.04 | 1.03 | [0.72,1.48] | 0.87 |
| Sex | ||||||
| Female | ref | |||||
| Male | 1.44 | [1.09,1.89] | 0.01 | 1.42 | [1.06,1.89] | 0.02 |
| Region of Origin | ||||||
| Sub-Saharan Africa | ref | ref | ||||
| South-eastern Asia | 1.18 | [0.85,1.66] | 0.32 | 1.07 | [0.75,1.54] | 0.69 |
| Southern Asia | 0.97 | [0.69,1.37] | 0.86 | 1.05 | [0.71,1.54] | 0.82 |
| Western Asia | 0.76 | [0.46,1.28] | 0.30 | 0.98 | [0.57,1.69] | 0.93 |
| Other | 0.80 | [0.40,1.61] | 0.53 | 0.87 | [0.42,1.78] | 0.70 |
| Smoking History | ||||||
| No | ref | |||||
| Yes | 0.8 | [0.45,1.41] | 0.44 | |||
| Flu Shot Received | ||||||
| No | ref | |||||
| Yes | 0.95 | [0.73,1.24] | 0.73 | |||
| Distance to TB Clinic, miles | 0.92 | [0.85,1.00] | 0.04 | 0.91 | [0.83,0.99] | 0.04 |
| Time to Appointment, days | ||||||
| Screened after 11 vs 28 days | 0.96 | [0.55,1.68] | 0.90 | 1.01 | [0.63,1.60] | 0.98 |
| Screened after 14 vs 28 days | 0.96 | [0.70,1.27] | 0.71 | 1.02 | [0.74,1.40] | 0.91 |
| Ageb | 0.99 | [0.98,1.00] | 0.04 | 0.99 | [0.98,1.00] | 0.28 |
aElixhauser Comorbidity Score and individual comorbidities were run in separate models
bOdds expressed as change per one year increase in age