Table 3.
PD risk predicted by the combination of falling history and depressive symptoms
| Total number | Number of PD occurrence | Person-years | Incidence Ratea (1/1000) | Adjusted HRb (95% CI) | |
|---|---|---|---|---|---|
| Total | |||||
| Falling (−) Depression (−) | 834,857 | 3522 | 3,515,446.76 | 1.002 | 1.00 |
| Falling (−) Depression (+) | 107,693 | 598 | 467,281.91 | 1.280 | 1.27 (1.16–1.38) |
| Falling (+) Depression (−) | 44,523 | 213 | 188,440.86 | 1.130 | 1.11 (0.97–1.28) |
| Falling (+) Depression (+) | 19,297 | 138 | 81,771.04 | 1.688 | 1.66 (1.40–1.97) |
| Men | |||||
| Falling (−) Depression (−) | 409,661 | 1657 | 1,706,433.44 | 0.971 | 1.00 |
| Falling (−) Depression (+) | 42,743 | 227 | 183,166.81 | 1.239 | 1.28 (1.11–1.47) |
| Falling (+) Depression (−) | 14,777 | 86 | 62,030.75 | 1.386 | 1.41 (1.14–1.76) |
| Falling (+) Depression (+) | 6136 | 40 | 25,498.32 | 1.569 | 1.60 (1.17–2.20) |
| Women | |||||
| Falling (−) Depression (−) | 425,196 | 1865 | 1,809,013.32 | 1.031 | 1.00 |
| Falling (−) Depression (+) | 64,950 | 371 | 284,115.10 | 1.306 | 1.25 (1.12–1.40) |
| Falling (+) Depression (−) | 29,746 | 127 | 126,410.11 | 1.005 | 0.97 (0.81–1.16) |
| Falling (+) Depression (+) | 13,161 | 98 | 56,272.72 | 1.742 | 1.67 (1.36–2.04) |
aIncidence rates were expressed as per 1000 person-years.bHRs were adjusted for sex, smoking, alcohol consumption, regular exercise, household income status, body mass index and the presence of hypertension, diabetes mellitus and hypercholesterolemia
Abbreviations: CI confidence interval, HR hazard ratio