Figure 5.

Genetic background influences resilience to toxicity caused by isoflurane/O₂ after traumatic brain injury (TBI). The percent change in mortality caused by post-exposure to isoflurane (ISO)/O₂ for each of 141 fly lines from the Drosophila Genetic reference Panel (DGRP). Genome-wide association study (GWAS) identified single nucleotide polymorphisms (SNPs) in Drip, Prip, and Gyc88E as being associated with the change in percent mortality at the indicated level of significance. Coloured dots indicate DGRP lines that contain significant SNPs.