Table 1. Effects of Phyllanthus amarus Extract and Esculetin on Glycosylated Haemoglobin (%) in STZ-Induced Diabetic Rats.

Groups	NC	DC	% Change from Control	D+PAE	% Change from Control	D+ESC	% Change from Control	PAE	% Change from Control	ESC	% Change from Control
HbA1c (%)	4.78± 0.33	8.31± 0.21#	–73.84	5.87± 0.17*	–22.80	6.23± 0.36**	–0.42	4.80± 0.34	–0.41	4.88± 0.35	–0.20

Abbreviations: NC, normal control; DC, diabetic control; D, diabetic; PAE, Phyllanthus amarus extract; ESC, esculetin; STZ, streptozotocin.

Note: The significant differences in between the groups were compared using one-way ANOVA followed by t-test. Data presented as Mean ± SEM (n = 6).

^#P < 0.001 against normal group and *p, **p < 0.001 against diabetic group.