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Significant Reactome and KEGG pathway enrichment among the 160 genes significantly downregulated by COVID-19 only in Old macaques.
| Pathway ID | Pathway description | Total pathway size | # Significant genes | FDR-corrected P value |
|---|---|---|---|---|
| Reactome | ||||
| R-HSA-4420097 | VEGFA-VEGFR2 Pathway | 99 | 7 | 0.037 |
| R-HSA-194138 | Signaling by VEGF | 107 | 7 | 0.037 |
| KEGG | ||||
| KEGG:04611 | Platelet activation | 122 | 8 | 2.5E-03 |
| KEGG:05206 | MicroRNAs in cancer | 158 | 8 | 0.016 |
