Table 1.
Respiratory parameters for all patients before and after sarilumab administration
| Patient | Date of start of symptoms | Date of hospitalization | Initial PaO2:FiO2 | Date(s) of sarilumab administration | PaO2:FiO2 after sarilumab |
| 1 | March 15, 2020 | March 25, 2020 | 83 | March 26, 2020 March 27, 2020 |
135 at d+1 185 at d+3 after second dose |
| 2 | March 15, 2020 | March 25, 2020 | 120 | March 27, 2020 | 296 at d+1 |
| 3 | March 18, 2020 | March 24, 2020 | 180 | March 27, 2020 | 290 at d+1 305 on April 4, 2020 |
| 4 | March 15, 2020 | March 28, 2020 | 192 | March 30, 2020 | 230 at d+1 330 on April 10, 2020 |
| 5 | March 18, 2020 | March 25, 2020 | 200 | March 26, 2020 | 270 at d+1 370 on April 10, 2020 |
| 6 | March 17, 2020 | March 27, 2020 | 240 | March 30, 2020 | 320 at d+1 |
| 7 | March 14, 2020 | March 26, 2020 | 90 | March 27, 2020 March 28, 2020 |
62 at d+1 |
| 8 | March 15, 2020 | March 25, 2020 | 178 | March 30, 2020 March 31, 2020 |
290 at d+1 |
| 9 | March 18, 2020 | March 26, 2020 | 70 | March 27, 2020 | 260 after administration |
| 10 | March 13, 2020 | March 23, 2020 | 137 | April 3, 2020 | 290 at d+1 330 on April 27, 2020 |
| 11 | March 12, 2020 | March 26, 2020 | 120 | 27 March 2020 | 178 at d+1 234 at d+4 382 at d+10 |
| 12 | March 18, 2020 | March 26, 2020 | 60 | March 27, 2020 | 290 after administration |
| 13 | March 15, 2020 | March 25, 2020 | 122 | March 26, 2020 | 72 at d+1 |
| 14 | March 21, 2020 | March 26, 2020 | 88 | March 27, 2020 | 92 at d+1 |
| 15 | March 23, 2020 | March 30, 2020 | 137 | March 31, 2020 | 290 at d+1 |
FiO2, fractional inspired oxygen; PaO2, arterial oxygen pressure.