Table 5.

Severity of HMPV disease in paediatric patients. HFNC = high flux nasal cannula; CO = conventional oxygenotherapy (low flow nasal cannula or oxygen mask); MV = mechanical ventilation.

Pediatric patients
Factor	Subgenotypes				Duplications vs other strains			A2c sublineage
	A2	B1	B2	p	A2c w/ duplication	Other strains	p	A2c w/ duplication	A2c w/o duplication	p
Length hospital stay	4.50 [3.00;7.75]	5.00 [4.00;7.00]	5.50 [3.00;7.25]	0.880	5.00 [4.00;11.00]	5.00 [3.00;7.00]	0.199	5.00 [4.00;11.0]	4.00 [3.00;6.00]	0.166
Respiratory support				1.000			0.297			0.406
Yes	47 (81.0 %)	27 (79.4 %)	19 (79.2 %)		14 (93.3%)	79 (78.2%)		14 (93.3 %)	25 (78.1 %)
Non	11 (19.0 %)	7 (20.6 %)	5 (20.8 %)		1 (6.67%)	22 (21.8%)		1 (6.67 %)	7 (21.9 %)
Type of respiratory support				0.520			0.140			0.391
HFNC	13 (22.4 %)	7 (20.6 %)	7 (29.2 %)		3 (20.0%)	24 (23.8%)		3 (20.0 %)	7 (21.9 %)
CO	28 (48.3 %)	20 (58.8 %)	10 (41.7 %)		8 (53.3%)	50 (49.5%)		8 (53.3 %)	16 (50.0 %)
MV	6 (10.3 %)	0 (0.00 %)	2 (8.33 %)		3 (20.0%)	5 (5.00%)		3 (20.0 %)	2 (6.25 %)
Non	11 (19.0 %)	7 (20.6 %)	5 (20.8 %)		1 (6.67%)	22 (21.8%)		1 (6.67 %)	7 (21.9 %)
Length respiratory support	3.00 [2.00;5.75]	4.00 [2.00;5.75]	3.00 [2.00;6.00]	0.874	3.00 [3.00;9.00]	4.00 [2.00;5.00]	0.208	3.00 [3.00;9.00]	3.00 [2.00;4.25]	0.122
ICU admission				0.031			0.633			1.000
Yes	9 (15.5 %)	0 (0.00 %)	2 (8.33 %)		2 (13.3%)	9 (8.9%)		2 (13.3 %)	5 (15.6 %)
Non	49 (84.5 %)	34 (100 %)	22 (91.7 %)		13 (86.7%)	92 (91.1%)		13 (86.7 %)	27 (84.4 %)
Length ICU stay	6.00 [4.00;7.00]	. [.;.]	13.0 [9.00;17.0]	0.340	9.00 [7.50;10.50]	5.00 [4.00;7.00]	0.340	9.00 [7.50;10.5]	4.00 [4.00;6.00]	0.155
Exitus				.			.			.
Yes	0 (0 %)	0 (0 %)	0 (0 %)		0 (0 %)	0 (0 %)		0 (0%)	0 (0%)
Non	58 (100 %)	34 (100 %)	24 (100 %)		15 (100%)	101 (100%)		15 (100 %)	32 (100 %)