Table 6.

Severity of HMPV disease in adult patients. HFNC = high flux nasal cannula; CO = conventional oxygenotherapy (low flow nasal cannula or oxygen mask); MV = mechanical ventilation

Adult patients
Factor	Subgenotypes				Duplications vs other strains			A2c sublineage
	A2	B1	B2	p	A2c w/ duplication	Other strains	p	A2c w/ duplication	A2c w/o duplication	p
Length hospital stay	4.00 [2.00;9.00]	9.00 [2.00;12.0]	4.00 [2.00;7.25]	0.327	4.00 [2.00;9.00]	6.00 [2.00;10.50]	0.442	4.00 [2.00;9.00]	2.50 [2.00;7.50]	0.787
Respiratory support				0.655			0.639			0.596
Yes	30 (90.9 %)	15 (88.2 %)	8 (80.0 %)		11 (84.6%)	42 (89.4%)		11 (84.6 %)	13 (92.9 %)
Non	3 (9.09 %)	2 (11.8 %)	2 (20.0 %)		2 (15.4%)	5 (10.6%)		2 (15.4 %)	1 (7.14 %)
Type of respiratory support				0.145			0.780			0.450
HFNC	4 (12.1 %)	1 (5.88 %)	1 (10.0 %)		2 (15.4%)	4 (8.5%)		2 (15.4 %)	1 (7.14 %)
CO	25 (75.8 %)	9 (52.9 %)	6 (60.0 %)		8 (61.5%)	32 (68.1%)		8 (61.5 %)	12 (85.7 %)
MV	1 (3.03 %)	5 (29.4 %)	1 (10.0 %)		1 (7.69%)	6 (12.8%)		1 (7.69 %)	0 (0.00 %)
Non	3 (9.09 %)	2 (11.8 %)	2 (20.0 %)		2 (15.4%)	5 (10.6%)		2 (15.4 %)	1 (7.14 %)
Length respiratory support	2.00 [1.00;5.00]	3.00 [1.00;10.0]	1.00 [1.00;5.50]	0.304	1.00 [1.00;4.00]	2.00 [1.00;6.00]	0.449	1.00 [1.00;4.00]	1.00 [1.00;4.25]	0.938
ICU admission				0.151			0.182			1.000
Yes	2 (6.06 %)	4 (23.5 %)	2 (20.0 %)		0 (0%)	8 (17%)		0 (0.00 %)	1 (7.14 %)
Non	31 (93.9 %)	13 (76.5%)	8 (80.0 %)		13 (100%)	39 (83%)		13 (100 %)	13 (92.9 %)
Length ICU stay	9.50 [6.75;12.2]	11.0 [5.00;21.0]	10.5 [8.75;12.2]	0.939	. [.;.]	10.5 [5.5;15.25]	.	. [.;.]	15.0 [15.0;15.0]	.
Exitus				0.096			1.000			1.000
Yes	2 (6.06 %)	1 (5.88 %)	3 (30.0 %)		1 (7.69%)	5 (10.6%)		1 (7.69 %)	1 (7.14 %)
Non	31 (93.9 %)	16 (94.1 %)	7 (70.0 %)		12 (92.3%)	42 (89.4%)		12 (92.3 %)	13 (92.9 %)