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. 2020 Aug 11;109(12):1531–1539. doi: 10.1007/s00392-020-01722-w

Table 4.

Stratification into patients with severe and non-severe course

Variable Non-severe course (n = 13) Non-severe course (n = 8) p value
Invasive mechanical ventilation 0 8 (100.0)  < 0.001
Age > 60 years 4 (30.8) 7 (87.5) 0.028
Reduced right ventricular function 1 (7.7) 5 (62.5) 0.014
New-onset arrhythmiasa 0 4 (50.0) 0.012
New thromboembolic eventsb 0 4 (50.0) 0.012
New-onset dialysis 2 (15.4%) 3 (37.5) 0.325
Mortality 0 7 (87.5)  < 0.001
White-cell count (/nl) 10.6 (± 4.6) 14.4 (± 7.5) 0.181
Lymphocyte count (%) 11.4 (± 5.3) 5.5 (± 3.5) 0.013
Platelet count (/nl) 222.0 (± 104.8) 395.1 (± 183.4) 0.017
C-reactive protein (mg/l) 102.5 (± 108.1) 181.8 (± 91.1) 0.116
Procalcitonin (ng/ml) 1.9 (± 2.4) 12.5 (± 9.8) 0.002
Lactate dehydrogenase (U/l) 421.8 (± 109.7) 983.0 (± 222.5)  < 0.001
Ferritin (µg/l) 2042.4 (± 2551.7) 4119.6 (± 616.0) 0.110
D-dimer (mg/l) 3.0 (± 2.0) 6.6 (± 3.5) 0.011
hs-cTnT (pg/ml) 93.9 (± 100.6) 234.8 (± 88.2) 0.017
NT-proBNP (ng/l) 2203.9 (± 1857.2) 21,162.5 (± 14,294.5)  < 0.001

Values are presented as mean ± standard deviation or as number and percentage

hs-cTnT high-sensitivity cardiac troponin T, n number, NT-proBNP N-terminal prohormone of brain natriuretic peptide

aArrhythmias included two patients with new-onset atrial fibrillation and two patients with new-onset ventricular tachycardia

bThromboembolic events included two patients with new deep vein thrombosis and two patients with new pulmonary embolism