TABLE II.

Clinical Outcomes and Complications

	Hip Procedures			Knee Procedures
	Hemophilia Cohort (N = 31)	Control Cohort (N = 943)	P Value*	Hemophilia Cohort (N = 87)	Control Cohort (N = 2,868)	P Value*
Thromboembolic complications (%)
Venous thromboembolism	0	0.64	1.000	1.15	0.98	0.581
Acute coronary syndrome (STEMI/NSTEMI/UA†)	0	0.95	1.000	0	0.28	1.000
Acute ischemic stroke/transient ischemic attack	0	0.21	1.000	0	0.24	1.000
Bleeding (%)
Bleeding complications	38.71	16.12	0.003	19.54	13.95	0.158
Intracerebral hemorrhage	0	0	—	0	0.03	1.000
Transfusion of red blood cells	19.35	7.74	0.034	12.64	4.05	0.001
Infection (%)
Surgical site infection	0	0.21	1.000	8.05	1.12	<0.001
Other infection	6.45	2.12	0.153	2.30	1.32	0.331
Discharge disposition (%)			0.442			<0.001
Home	70.97	76.25		67.82	64.19
Short-term care facility	16.13	8.70		29.89	15.27
Long-term care facility	12.90	14.42		1.15	19.56
Other	0	0.42		1.15	0.84
Hospice	0	0.11		0	0.03
Died in hospital	0	0.11		0	0.10
Median hospital length of stay (IQR)‡ (days)	6 (5)	3 (1)	<0.001	5 (4)	3 (2)	<0.001
Unplanned 30-day readmission (%)			<0.001			0.018
No	77.42	95.86		89.66	95.54
Yes	22.58	4.14		10.34	4.46

^*Fisher exact test.

^†STEMI = ST-elevation myocardial infarction, NSTEMI = non-ST-elevation myocardial infarction, and UA = unstable angina.

^‡After excluding 4 controls who died in the hospital.