Fig 3. The synchrony and the dimensionality in IO firings moderated by effective coupling.

A-B: The synchrony (A) and the dimensionality (B) for each of the three data conditions. Significance level, ns p > 0.05, * p < 0.05, ** p < 0.01. C: the change of synchrony by drugs (either CBX–green bars, or PIX–red bars, left axis) is coupled with change in the dimensionality (right axis) compared with the control level. Each connected pair of data points is from one animal. D–E: The synchrony (D) and the dimensionality (E) as functions of effective coupling strength averaged for selected neurons in individual animals confirming that effective coupling is a control parameter to optimize the synchrony and thus the dimensionality of IO firings. Each type of symbol represents the data of an individual animal. The cyan solid lines show results of the linear regression models and shaded regions are of 95% CIs.