TABLE 1.
The detailed information of the top 30 most different AS events
Symbol | AS type | Exons | MeanT | MeanN | logFC | P‐value |
---|---|---|---|---|---|---|
Upregulated | ||||||
GSTM2 | AT | 13 | 0.240 | 0.035 | 0.832 | 9.45E‐59 |
COL6A3 | ES | 6 | 0.273 | 0.104 | 0.417 | 3.18E‐56 |
COMT | AP | 3 | 0.179 | 0.027 | 0.828 | 2.68E‐54 |
L3MBTL4 | AT | 19 | 0.330 | 0.150 | 0.342 | 4.45E‐48 |
ALDH1L1 | AP | 1 | 0.660 | 0.059 | 1.046 | 3.08E‐44 |
GABARAP | RI | 1.2:1.3:1.4 | 0.021 | 0.006 | 0.549 | 3.94E‐43 |
ZNF331 | AP | 1 | 0.285 | 0.099 | 0.460 | 5.96E‐42 |
COL4A6 | AT | 52 | 0.135 | 0.021 | 0.801 | 2.03E‐41 |
PRUNE2 | AT | 7 | 0.089 | 0.002 | 1.586 | 9.68E‐41 |
ANO6 | AT | 25 | 0.087 | 0.032 | 0.432 | 9.55E‐40 |
LGALS3 | AT | 6 | 0.076 | 0.034 | 0.346 | 1.54E‐38 |
EMP2 | AP | 2 | 0.224 | 0.055 | 0.614 | 5.14E‐38 |
MATR3 | AP | 1 | 0.084 | 0.025 | 0.527 | 3.69E‐37 |
CKMT2 | ES | 2 | 0.283 | 0.096 | 0.472 | 7.88E‐37 |
MAGED2 | AP | 3 | 0.167 | 0.036 | 0.670 | 2.21E‐35 |
Downregulated | ||||||
ALDH1L1 | AP | 3 | 0.281 | 0.766 | −0.435 | 1.19E‐31 |
MTUS2 | AP | 7 | 0.140 | 0.711 | −0.706 | 2.69E‐23 |
OSBPL5 | AP | 1.1 | 0.345 | 0.728 | −0.324 | 4.02E‐20 |
VPS9D1 | AP | 1 | 0.266 | 0.597 | −0.351 | 4.05E‐17 |
RGS12 | AP | 7.1 | 0.226 | 0.529 | −0.370 | 6.46E‐17 |
PAK6 | AP | 2 | 0.112 | 0.450 | −0.602 | 1.16E‐16 |
DNMT3A | AT | 5.2 | 0.127 | 0.278 | −0.340 | 3.41E‐15 |
PRKAR1B | AP | 5 | 0.127 | 0.341 | −0.427 | 2.22E‐14 |
NFYC | AP | 4 | 0.068 | 0.151 | −0.349 | 2.87E‐14 |
KRT222 | AT | 5.2 | 0.016 | 0.073 | −0.652 | 3.91E‐14 |
TRIM16 | AP | 6.1 | 0.251 | 0.529 | −0.324 | 4.05E‐14 |
RGS3 | AP | 24 | 0.111 | 0.267 | −0.380 | 9.32E‐14 |
PDLIM5 | AT | 4 | 0.031 | 0.069 | −0.344 | 1.29E‐13 |
CTAGE5 | AP | 1 | 0.092 | 0.267 | −0.461 | 3.01E‐13 |
COX17 | AT | 7 | 0.098 | 0.24 | −0.391 | .00 |
The P‐value was calculated by t test.
Abbreviations: logFC, log2 fold change; MeanN, the mean PSI value in paired normal tissue; MeanT, the mean PSI value in prostate cancer tissue.