Fig. 6.

a NEFA concentration in serum from post-partum Jersey cows (11 ± 3 DIM) containing 0.32 mmol/L NEFA treated with physiological (22.5 U/mL) and supraphysiological (45 and 67.5 U/mL) concentrations of lipoprotein lipase for 24 h. b PPAR activation measured by gene reporter assay in MAC-T cells by serum samples with low (0.29 mmol/L), medium (0.58 mmol/L) and high (1.0 mmol/L) circulating NEFA, treated with two subphysiological, non-cytotoxic doses of LPL (0.81 and 1.62 U/mL). Asterisks reflect significant differences when compared with each group’s baseline (LPL = 0); colors refer to treatment group. Overall effect of treatments is indicated in the bottom-left corner of the panel