Table 3.
LCR16a type | Nonredundant sites | %GC (E, p value ± SE) | SINE (E, p value ± SE) | LINE (E, p value ± SE) |
---|---|---|---|---|
Donors | 63 | 1.07, 1.6 × 10−5 ± 0.0005 * | 1.47, 3.7 × 10−8 ± 2.4 × 10−5 * | 1.03, 0.2 ± 0.05 |
Acceptors | 27 | 1.11, 2 × 10−9 ± 6 × 10−6 * | 1.68, 7.9 × 10−6 ± 0.00038 * | 1.19, 0.009 ± 0.013 |
Pre-integration sites | 13 | 1.18, 0.09 ± 0.08 | 1.66, 0.0077 ± 0.024 | 1.29, 0.024 ± 0.04 |
Note: we corrected for multiple hypothesis testing using FWER for a total of nine tests. The associations that had a corrected p value + SE ≤ 0.05 are denoted with an asterisk “*” 10,000 permutations. The “E” value represents the enrichment coefficient that was calculated based on the observed value divided by the expected, where the latter was defined as the mean of 10,000 genome-wide permutations. The retrotransposon statistics refer to the enrichment in LINE and SINE counts relative to the distributed segments