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. Author manuscript; available in PMC: 2020 Aug 11.
Published in final edited form as: Vaccine. 2019 May 29;37(36):5474–5480. doi: 10.1016/j.vaccine.2019.04.079

Table 3:

Geometric mean concentration (GMC) of anti-pertussis toxin (PT) IgG in maternal and cord blood stratified by gestational week at Tdap vaccination and time interval between vacination and delivery.

Maternal anti-PT IgG
p-value* Cord blood anti-PT IgG
p-value* Ratio ** (95% CI)
N % GMC (95% CI) GMC (95% CI)
Gestational Week
Mean (SD) 30.1 (3.2)
17|-|26 21 8.6 72.7 (58.3-90.6) 0.764 114.3 (95.4-136.9) 0.060 1.6 (1.4-1.8)
27|-|29 87 35.8 64.5 (54.1-76.8) 100.1 (83.6-119.8) 1.5 (1.4-1.7)
30|-|33 97 40.0 64.6 (54.4-76.6) 84.9 (72.2-99.9) 1.3 (1.2-1.4)
34|-|40 38 15.6 73.7 (56.9-95.4) 70.4 (51.7-96.1) 1.0 (0.8-1.1)
Time interval between vaccination and delivery (days)
Mean (SD) 65.0 (22.1)
15|-|30 17 7.0 74.7 (50.2-111.2) 0.411 54.0 (34.4-84.8) 0.006*** 0.8 (0.6-0.9)
31|-|60 77 31.7 66.4 (54.8-80.6) 82.8 (68.2-100.5) 1.2 (1.1-1.3)
61|-|90 128 52.7 62.9 (54.7-72.3) 93.6 (81.7-107.2) 1.5 (1.4-1.6)
≥ 91 21 8.6 86.1 (64.8-114.7) 141.2 (101.1-197.1) 1.6 (1.4-1.9)
*

Kruskal Wallis test

**

p<0.001

***

15|-|30 vs 61|-|90 p= 0.014; 15|-|30 vs ≥ 91p= 0.001; 31|-|60 vs ≥ 91 p= 0.016