Table 1.
Summary of studies included in the systematic review.
| Author (year) | Study design | Sample number (n) | Comparitors | Average Age (years) | Perioperative Complication Rate (%) | Postoperative complication Rate (%) | Overall Complication rate (%) | Average Length of Stay (days) | Average Operative Duration (minutes) | Cost (euros) |
|---|---|---|---|---|---|---|---|---|---|---|
| Endoloops | ||||||||||
| Beldi (2006) | Prospective | 2565 | EL vs Staple | 28 | 1.10% | 5.30% | 6.40% | 5.4 | 53.4 | 16 |
| Rakic (2014) | Prospective | 163 | EL vs Staple | 26 | 0.61% | 4.90% | 5.51% | 4.0 | 48 | 554.9 |
| Swank (2014) | Retrospective | 571 | EL vs Staple | 34 (med) | 6.70% | 9.80% | 16.50% | 2 | 60 | n/a |
| Sahm (2010) | Prospective | 1135 | EL with selective staple | 32 | 4.32% | 1.94% | 6.26% | n/a | 47.33 | n/a |
| Kiudelis (2013) | Prospective | 112 | EL vs suture | 32.4 | 3.60% | 6.30% | 9.90% | 2.4 | 58.4 | 460 |
| Delibegovic (2009) | Prospective | 24 | EL vs Polymeric clip | 28.7 | 0.00% | 0 | 0.00% | 2.2 | 47.1 | 88.5 |
| Colak (2013) | RCT | 27 | EL vs Polymeric clip | 26.8 | 0 | 11.1% | 11.10% | 2.5 | 75.4 | 35.12 |
| Jenwitheesuk (2012) | Retrospective | 23 | EL vs Polymeric clip | 26 | 3.85% | 0 | 3.85% | 3.17 | 66 | n/a |
| Lucchi (2017) | Retrospective | 121 | EL vs Polymeric clip | 29.9 | 0 | 1.65% | 1.65% | 1.2 | 40.5 | 92 |
| Wilson (2018) | Retrospective | 78 | EL vs polymeric clip | 28.2 | 0 | 5.1% | 5.1% | 2.9 | 68 | 24.36 |
| Kim (2018) |
Retrospective |
75 |
EL vs Staple |
38.3 |
0 |
18.6% |
18.6% |
0.7 |
38.5 |
1680 |
|
Staple | ||||||||||
| Beldi (2006) | Prospective | 3281 | Staple vs EL | 30 | 1.30% | 5.90% | 7.20% | 5.9 | 51.7 | 306 |
| Rakic (2014) | Prospective | 75 | Staple vs EL | 38 | 1.33% | 9.33% | 10.66% | 3.6 | 55 | 970.7 |
| Swank (2014) | Retrospective | 465 | Staple vs EL | 36 | 10% | 8.60% | 18.60% | 2 | 58 | n/a |
| Sahm (2010) | Prospective | 43 | Selective staple vs EL | 46 | 2.32% | 6.98% | 9.30% | n/a | 76.6 | n/a |
| Hanssen (2007) | Prospective | 14 | Staple vs Polymeric clip | n/a | 0 | 0 | 0.00% | 2.78 | 62.4 | 264.92 |
| Al-Temimi (2017) | Prospective | 47 | Staple vs Polymeric clip | 32.1 | 6.38% | 19.1% | 25.5% | 2.5 | 38.8 | 259.64 |
| Kim (2018) | Retrospective | 250 | Staple vs EL | 38.2 | 0 | 24.0% | 24.0% | 1.1 | 42.4 | 2005 |
| Kliuchanok (2019) |
Retrospective |
410 |
Staple vs Polymeric clip |
41.7 |
2.2% |
7.6% |
9.8% |
3.7 |
55.3 |
348.7 |
|
Clip | ||||||||||
| Colak (2013) | RCT | 26 | Polymeric clip vs EL | 31.9 | 0 | 11.50% | 11.5% | 2.1 | 64.7 | 8.78 |
| Delibegovic (2009) | Prospective | 28 | Polymeric clip vs EL | 26.6 | 3.57% | 0% | 3.6% | 2.2 | 38.7 | 76.9 |
| Hanssen (2007) | Prospective | 14 | Polymeric clip vs Staple | n/a | 0.00% | 0% | 0.0% | 2 | 53.4 | 192.82 |
| Jenwitheesuk (2012) | Retrospective | 68 | Polymeric clip vs EL | 32 | 2.94% | 0% | 2.9% | 2.5 | 38 | n/a |
| Strzalka (2014) | Retrospective | 93 | Metal clips | 33.6 | 0.00% | 7% | 7.0% | 3.38 | 66 | n/a |
| Gonenc (2012) | RCT | 61 | Metal clip vs suture | 26.76 | 1.60% | 4.8% | 6.4% | 0.796 | 46.3 | n/a |
| Rickert (2012) | Prospective | 100 | Metal clip | 30.6 | 0.00% | 3% | 3.0% | 4 | 54 | n/a |
| Alis (2012) | Retrospective | 233 | Metal clip | 28.4 | 3.00% | 5% | 8.0% | 0.75 | 31.1 | 3.50 |
| Ates (2012) | RCT | 30 | Metal clip vs suture | 28.23 | 20.0% | 3% | 23.0% | 2.07 | 41.3 | n/a |
| Al-Temimi (2017) | Prospective | 45 | Polymeric clip vs Staple | 27.97 | 11.10% | 2.20% | 13.30% | 1.8 | 43.3 | 29.38 |
| Lucchi (2017) | Retrospective | 138 | Polymeric clip vs EL | 32.8 | 0 | 2.17% | 2.17% | 1.23 | 36.4 | 48 |
| Wilson (2018) | Retrospective | 47 | Polymeric clip vs EL | 32.1 | 0 | 4.26% | 4.26% | 3.2 | 59.0 | 24.36 |
| Kliuchanok (2019) |
Retrospective |
208 |
Polymeric clip vs Staple |
33.6 |
1.0% |
1.4% |
2.4% |
2.9 |
51.0 |
19.94 |
|
Suture | ||||||||||
| Kiudelis (2013) | Prospective | 40 | Suture vs EL | 32.1 | 2.50% | 5% | 7.5% | 2.8 | 79.6 | n/a |
| Ates (2012) | RCT | 31 | Suture vs Metal Clip | 29.35 | 13% | 10% | 23.0% | 2.06 | 62.81 | n/a |
| Gonenc (2012) | RCT | 46 | Suture vs Metal Clip | 27.4 | 4.20% | 8.50% | 12.70% | 0.846 | 61.9 | n/a |