Fig. 3. Characteristics of HPO term lists extracted from patient EHRs are correlated with characteristics of resultant variant shortlists.
Each case is represented by one point. a The number HPO terms extracted at enrollment is positively correlated with the number of Moon variants on the resultant variant shortlist (r = 0.40, p = 0.005). b The number HPO terms extracted at reanalysis is positively correlated with the number of Moon variants on the resultant shortlist (r = 0.41, p = 0.0032). c The change in input HPO term list size between enrollment and reanalysis is positively correlated with the change in resultant variant shortlist size (r = 0.48, p = 0.0005), as well as with d variant shortlist turnover (r = 0.57, p < 0.0001).