Remimazolam has very low oral bioavailability of 1.2–2.2%.

Oral remimazolam up to 480 mg has no clear pharmacodynamic effects.

Alcohol dose-dependently increases exposure to remimazolam (up to two times).

Oral co-administration of alcohol and remimazolam shows mild pharmacodynamic effects.

Remimazolam has no potential for misuse in drug-facilitated sexual assaults.