Table 3.

Correlation between anti-malarial drug 50% maximal inhibitory concentration values

Drug pairing	Number of experiments	Correlation coefficient (r)	p value
AQ vs CQ	74	0.517	< 0.001
AQ vs DHA	68	− 0.28	0.01
AQ vs LUM	73	− 0.45	< 0.001
AQ vs MQ	74	− 0.04	0.72
AQ vs PPQ	74	0.07	0.55
AQ vs QN	73	0.80	< 0.001
CQ vs DHA	70	0.096	0.41
CQ vs LUM	73	0.036	0.76
CQ vs MQ	76	0.29	0.008
CQ vs PPQ	75	0.21	0.06
CQ vs QN	73	0.49	< 0.001
DHA vs LUM	67	0.30	0.01
DHA vs MQ	70	0.35	0.002
DHA vs PPQ	68	0.43	< 0.0001
DHA vs QN	67	− 0.35	0.002
LUM vs MQ	74	0.5	< 0.001
LUM vs PPQ	73	0.11	0.34
LUM vs QN	71	− 0.36	0.002
MQ vs PPQ	75	0.45	< 0.001
MQ vs QN	73	− 0.02	0.87
PPQ vs QN	72	− 0.10	0.37

Significant correlation values are highlighted in bold

AQ amodiaquine, CQ chloroquine, DHA dihydroartemisinin, LUM lumefantrine, MQ mefloquine, PPQ piperaquine, QN quinine