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. 2020 Aug 11;11:4018. doi: 10.1038/s41467-020-17840-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Cohort-specific co-abundances identified for three key species in the IBD cohort, involving 33 IBD-specific co-abundances. Each dot indicates one species. Red indicates IBD key species. Each line represents one IBD-specific co-abundance relationship. b Cohort-specific co-abundances identified for four key pathways in IBD and one key pathway in 300OB, involving 385 cohort-specific co-abundances. Each line represents a cohort-specific correlation between two pathways. Yellow lines represent obesity-specific co-abundances. Grey lines represent IBD-specific co-abundances. Each dot indicates one pathway. Pathways belonging to the same metabolic category have the same colour and are clustered as sub-circles. Colour legends are shown in the plot.