Fig. 1.

Sex-specific changes in blood glucose and body weight of mice after streptozotocin treatment. Changes in blood glucose level (A) and body weight (B) in female mice treated with streptozotocin; Changes in blood glucose level (C) and body weight (D) in male mice treated with streptozotocin. Group: CON, normal control mice; T1D, streptozotocin-induced type 1 diabetic mice. Gender: ♀, female; ♂, male. Data are presented as mean ± SEM (n = 6 for each group). The differences in blood glucose level and body weight between CON and T1D mice were analyzed by repeat-measurement ANOVA. Significant level: ***P < 0.001; n.s., no significant.