Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 31;18:2063–2074. doi: 10.1016/j.csbj.2020.07.019

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 4 — Diabetes-driven shifts in metabolic patterns in different brain regions of male mice. OPLS-DA score plots and VIP values based on the (A) hippocampus (R² = 0.946, Q² = 0.831), (B) cortex (R² = 0.908, Q² = 0.712), (C) cerebellum (R² = 0.955, Q² = 0.882), (D) striatum (R² = 0.966, Q² = 0.873), (E) hypothalamus (R² = 0.984, Q² = 0.920) and (F) midbrain (R² = 0.967, Q² = 0.863) metabolomes between normal control (CON) and type 1 diabetic (T1D) mice. Metabolite abbreviation: ADP, adenosine diphosphate; Ala, alanine; AMP, adenosine monophosphate; Asp, aspartate; Cho, choline; Cre/pCre, creatine/phosphocreatine; GABA, γ-Aminobutyric acid; Gln, glutamine; Glu, glutamate; Gly, glycine; IMP, inosine monophosphate; Ino, inosine; Lac, lactate; Myo, myo-inositol; NAA, N-acetylaspartate; NAD+, nicotinamide adeninedinucleotide; Suc, succinate; Tau, taurine.