Fig. 7.

The interaction effect of gender and diabetes on metabolic changes in the cortex of mice. (A) Tau, taurine; (B) Lac, lactate; (C) Myo, myo-inositol; (D) Gln, glutamine. Metabolites described herein indicate a significant interaction effect between gender and diabetes based on the linear mixed model analysis (P < 0.05). Data are obtained from mixed-model analysis and presented as least-square-mean ± SEM (n = 6 for each group). Different lowercase letters represent significant differences (P < 0.05). Gender: Red line, female mice; Blue, male mice. Group: CON, normal control mice; T1D, type 1 diabetic mice. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)