Fig. 8.

Sex-specific metabolic pathway changes in different brain regions of mice after streptozotocin treatment. The colored dots represent metabolic pathways that include one or more metabolites with a significant difference (P < 0.05) between normal control and diabetic mice, and the dot size is in proportion to the number of metabolites. Brain region: Hip, hippocampus; Cor cortex; Str, striatum; Cer, cerebellum; Hyp, hypothalamus; Mid, midbrain. Gender: ♀, female; ♂, male. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)