Table 4.
Unadjusted | Adjusteda | |||
---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p value | |
Age | 1.065 (1.039–1.090) | <0.001 | 1.060 (1.034–1.087) | < 0.001 |
Sex | 0.812 (0.535–1.233) | 0.329 | ||
BMI | 0.969 (0.914–1.027) | 0.291 | ||
Symptom | 1.271 (0.839–1.926) | 0.258 | ||
Alcohol history | 1.075 (0.646–1.789) | 0.781 | ||
Smoking history | 1.457 (0.976–2.177) | 0.066 | ||
GGO (yes) | 1.033 (0.597–1.787) | 0.907 | ||
CCI (>2) | 1.195 (0.765–1.867) | 0.434 | ||
Coagulopathyb | 3.867 (2.468–6.057) | <0.001 | 3.380 (2.053–5.566) | < 0.001 |
Intrapulmonary metastasis (yes) | 3.625 (1.913–6.866) | <0.001 | 3.329 (1.556–7.125) | 0.002 |
Lymph node metastasis (yes) | 1.425 (0.954–2.129) | 0.084 | ||
Distant metastasis (yes) | 1.757 (1.068–2.890) | 0.027 | 0.857 (0.455–1.614) | 0.633 |
Histological type | 0.148 | |||
Adenocarcinoma | 3.697 (0.863–15.833) | 0.078 | ||
Squamous-cell carcinoma | 3.806 (0.873–16.598) | 0.075 | ||
Clinical stagec | 1.492 (0.990–2.250) | 0.056 |
Notes: aMultivariate model included all variables that were associated with elevated PASP at univariate analyses. bCoagulopathy (dichotomous). cClinical stage (dichotomous).