Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 16;15(2):424–438. doi: 10.1016/j.stemcr.2020.06.013

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

JMJD1A and JMJD1B Are Required for Maintenance of the Male Germline

(A–F) Histological analysis of testes and epididymis of 3-month-old male mice of the genotypes indicated above each figure (A) to (F). Paraffin-embedded testis and epididymis sections were stained with PAS-hematoxylin and hematoxylin-eosin, respectively. Enlarged views of testes sections (boxed areas in the top panel) are shown in the middle panel. Scale bars, 100 μm.

(G) Population analysis of testicular cells in 3-month-old testes of the indicated genotypes. The number of cells per PAS-hematoxylin-stained cross-tubular section is presented. Testicular cells were classified into six types according to their PAS-hematoxylin-staining profile, morphology, and intratubular localization. Abnormal cells represent those that could not be classified. More than 10 tubular sections were analyzed per sample.

(H) Summary of the developmental phenotypes of male germ cells lacking Jmjd1a and/or Jmjd1b alleles. Terminal developmental stages of male germ cells of the indicated genotypes are illustrated.