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. 2020 Jul 16;15(2):439–453. doi: 10.1016/j.stemcr.2020.06.015

Figure 3.

Figure 3

UTX Loss-of-function Inhibits Neural Differentiation of hESCs

(A) Immunostaining of neuron markers MAP2 and Tuj1 at day 40 of neural differentiation. Scale bar, 20 μm.

(B) Quantitative analysis showing reduced percentages of MAP2+ and Tuj1+ neurons derived from UTX KO hESCs.

(C) qRT-PCR analysis showing that the expression levels MAP2 and Tuj1 were significantly lower in UTX KO cells at day 40 of neural differentiation. Results are presented as mean ± SEM; n = 3 independent experiments. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.