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. Author manuscript; available in PMC: 2021 Aug 5.
Published in final edited form as: Neuron. 2020 Jun 16;107(3):580–589.e6. doi: 10.1016/j.neuron.2020.05.007

Figure 2. Disused somatomotor cortex became functionally uncoupled from opposite hemisphere.

Figure 2.

(A) Seed maps showing functional connectivity (FC) of each voxel with the left primary somatomotor cortex (L-SM1ue) during scans acquired before, during and after casting (Pre, Cast, Post) in an example participant (Ashley). The L-SM1ue region of interest (ROI) was defined using task functional MRI. (B) Daily time course of FC between L-SM1ue and R-SM1ue for each participant. Δr values are based on a time-varying exponential decay model (black lines, dr⁄dt = α(r∞ − r); Nico: P = 0.002, Ashley: P < 0.001, Omar: P<0.001). (C and D) Daily time course of FC in lower extremity (C) and face (D) regions of the left and right somatomotor cortex.