Figure 2.

Primary Cilia Deficits Are Not Observed in the CA1 and CA3 Regions of the Hippocampus, and S1 and EC of the Cortex in Fmr1 KO Mice

(A–D) Left: immunostaining of AC3 (magenta) with DAPI nuclear staining (green) in the brains of P60 WT or Fmr1 KO mice. The (A) hippocampal CA1 (CA1), (B) hippocampal CA3 (CA3), (C) somatosensory cortex (S1), and (D) entorhinal cortex (EC) were imaged and higher magnifications of the left images (yellow boxes) are shown in the middle and right panels. Right: quantification of the percentage of AC3⁺ cells among DAPI⁺ cells in the indicated brain region.

n = 8, mean ± SEM. Student's unpaired t test.