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. 2020 Jul 23;15(2):482–497. doi: 10.1016/j.stemcr.2020.06.019

Figure 3.

Figure 3

Evaluation of the Retinal Impact of Exposure to a CW Laser and an Ultrafast Laser Using SLO and OCT

(A and B) Conventional SLO (A) and a spectral-domain OCT scan (B) of a monkey retina ablated with a CW laser at 6 weeks post exposure. At the lesion site, there is complete ablation of the outer retina with apposition of the inner plexiform layer to the RPE. The RPE is irregular with overlying scattered hyperreflective foci. OCT scan was acquired in the area designated by the blue line in (A).

(C and D) SLO (C) and a spectral-domain OCT scan (D) of a monkey retina ablated using an ultrafast laser with adaptive optics at 6 weeks post exposure. OCT imaging shows localized disruption within the outer limiting membrane and the outer nuclear layer. The linear dimension of an exposure area is shown on the OCT scan. OCT was acquired across the blue line in (C). White arrows in (C) highlight the pattern of ultrafast laser lesions.