Table 3. The frequencies of HVEM rs2234167, IL-4 rs2070874, rs2243263, and IL-10 rs1800896 and rs1800872 polymorphisms in different ESCC subgroups.

Genotype	Overall cases (n=721)		Stage I/II patients (n=328)		Stage III/IV patients (n=393)		Controls (n=1208)
	n	%	n	%	n	%	n	%
HVEM rs2234167 G>A
GG	668	93.30	302	92.92	366	93.61	1,117	93.01
GA	47	6.56	23	7.08	24	6.14	81	6.74
AA	1	0.14	0	0.0	1	0.26	3	0.25
A allele	49	3.42	23	3.54	26	3.32	87	3.62
IL-4 rs2070874 T>C
TT	486	67.88	223	68.62	263	67.26	780	64.95
TC	214	29.89	96	29.54	118	30.18	371	30.89
CC	16	2.23	6	1.85	10	2.56	50	4.16
C allele	246	17.18	108	16.62	138	17.65	471	19.61
IL-4 rs2243263 G>C
GG	615	86.13	282	87.04	333	85.38	1,048	87.26
GC	96	13.45	41	12.65	55	14.10	149	12.41
CC	3	0.42	1	0.31	2	0.51	4	0.33
C allele	102	7.14	43	6.64	59	7.56	157	6.54
IL-10 rs1800872 T>G
TT	349	48.81	161	49.54	188	48.21	550	45.80
TG	301	42.10	136	41.85	165	42.31	523	43.55
GG	65	9.09	28	8.62	37	9.44	128	10.65
G allele	431	30.14	192	29.54	239	30.64	779	32.43
IL-10 rs1800896 T>C
TT	625	87.66	280	86.42	345	88.69	1,061	88.34
TC	84	11.78	42	12.96	42	10.80	136	11.32
CC	4	0.56	2	0.62	2	0.51	4	0.34
C allele	92	6.45	46	7.10	46	5.91	144	6.00